Complex Therapeutics

Mithra has an extensive expertise in the development of complex and long-acting innovative products using medical polymer technology.

Mithra has developed the contraceptive vaginal ring Myring® and Tibelia®, a tablet composed of tibolone used for hormone therapy in menopause. It focuses now on the development of a biodegradable subcutaneous implant, Zoreline®, for hormone-dependent cancers.

What is long-acting technology?

Polymer technology allows prolonged drug delivery based on the use of polymer matrices. These enable a drug’s active pharmaceutical ingredient (API) to be distributed at a predetermined rate over a period of time (from 1 month to 5 years), maintaining controlled drug delivery with minimum side effects. 

It is used for various drug delivery strategies: intra-uterine devices, vaginal rings or implants. Little to no action is required by the patient, which improves compliance and therefore yields better results.

Complex Therapeutics portfolio

Myring®

Myring® is a contraceptive vaginal ring made of ethylene-vinyl-acetate (EVA) copolymers which releases a combination of hormones.

Myring® has been marketed in Europe and Canada and will be launched in the United States by early 2023.

Myring®

On the market

Tibelia®

Tibelia® is a tablet composed of tibolone, a synthetic steroid used for hormone therapy.

Tibelia® is already commercialized worldwide.

Tibelia®

On the market

Zoreline®

Zoreline® is a biodegradable subcutaneous implant for prostate cancer, breast cancer and benign gynecological indications (endometriosis, uterine fibroids). Mithra is currently developing a one-month implant (3.6 mg goserelin) and a 3-month implant (10.8 mg goserelin).

Zoreline®

Formulation

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